GHRP-6 Acetate (5mg)

Description

GHRP-6 Acetate (His-D-Trp-Ala-Trp-D-Phe-Lys-NH₂, 5mg) is a synthetic hexapeptide growth hormone secretagogue and one of the first-generation GHSR-1a agonists developed from enkephalin research. It stimulates GH release through the ghrelin pathway and was a foundational compound in establishing GH secretagogue pharmacology. The 5mg quantity is suited for preliminary receptor studies and dose-finding experiments.

Why Researchers Select GHRP-6

GHRP-6 was the original template compound for understanding GH secretagogue pharmacology and remains a reference standard. Unlike second-generation compounds like Ipamorelin, GHRP-6 stimulates both GHSR-1a and produces dose-dependent cortisol, ACTH, and prolactin release — making it the preferred model compound when researchers specifically want to study GH secretagogue-induced HPA axis co-activation. It also potently stimulates appetite through hypothalamic NPY upregulation, providing a research tool for ghrelin pathway-appetite axis studies.

Common Research Applications

• GHSR-1a pharmacology reference compound studies
• GH/cortisol/ACTH co-stimulation pathway research
• Ghrelin pathway-appetite (NPY) axis investigation
• First-generation vs. second-generation GH secretagogue comparison

Molecular Profile

• Sequence: His-D-Trp-Ala-Trp-D-Phe-Lys-NH₂ | MW: ~873.0 g/mol
• CAS: 87616-84-0 | Purity: ≥98% HPLC

For Research Use Only. Not for human or veterinary use.