5-Amino-1MQ (50mg)

Original price was: $220.00.Current price is: $89.00.

5-Amino-1MQ (50mg) is a research-use product for laboratory studies involving metabolic pathways, energy-balance models, and structured workflow design.

SKU: YPB.247 Category:

Description

5-Amino-1-methylquinolinium (5-Amino-1MQ, 50mg) is a small-molecule nicotinamide N-methyltransferase (NNMT) inhibitor supplied in bulk quantity for extended research protocols. The 50mg format is intended for multi-arm dose-response curves, longitudinal metabolic studies, or parallel investigation across multiple cell model systems.

Why Researchers Select 5-Amino-1MQ

NNMT is overexpressed in adipose tissue in obesity models and catalyzes the methylation of nicotinamide, depleting the SAM pool available for other methylation reactions. By inhibiting NNMT, 5-Amino-1MQ conserves SAM and shifts NAD⁺/NADH ratios. In 3T3-L1 adipocyte studies, NNMT inhibition has been shown to reduce lipid accumulation and influence gene expression patterns associated with adipogenesis. The 50mg quantity supports consistent supply across extended study timelines.

Common Research Applications

  • Multi-arm NNMT inhibition dose-response studies
  • Longitudinal adipogenesis and lipid metabolism investigation
  • NAD⁺ pathway research requiring larger working volumes
  • Comparative metabolic model experiments

Molecular Profile

  • MW: ~179.6 g/mol | Form: Lyophilized powder | Purity: ≥99% HPLC

For Research Use Only. Not for human or veterinary use.

Additional information

Weight 0.2 lbs
Dosage

5mg, 50mg

Storage Instructions

All our research peptides are manufactured using a lyophilization (freeze-drying) process. This method is designed to maintain product integrity and allows vials to remain stable during shipping for approximately 3–4 months.

Once a vial is reconstituted with bacteriostatic water, it should be stored in the refrigerator to help maintain stability. Under these conditions, reconstituted material is generally considered stable for up to 30 days.

Lyophilization is a dehydration technique in which compounds are frozen and then exposed to low pressure. This causes the water in the vial to sublimate directly from solid to gas, leaving behind a stable, crystalline white structure. This powder can be kept at room temperature until reconstitution.

Upon receipt, products should be stored away from heat and light. For short-term use, refrigeration at approximately 4°C (39°F) is suitable. For long-term storage (several months to years), vials may be placed in a freezer at approximately -80°C (-112°F). Freezing is the preferred method for preserving product stability over extended periods.

⚠️ Important Notice: These products are intended for research use only. Not for human consumption.

Certificate of Analysis

Every batch undergoes rigorous third-party laboratory testing to verify identity, purity (≥98%), and quality before release.

View Certificate of Analysis
Third-Party Verified ≥98% Purity HPLC & MS Tested
You are unable to view this website.

⚠️ Research Use Only — Legal Acknowledgment

All products on this website are sold strictly for in vitro research and laboratory use only.

  • Not for human or veterinary use, consumption, or application
  • Not FDA-approved to diagnose, treat, cure, or prevent any disease
  • Buyer assumes full responsibility for legal compliance in their jurisdiction

By clicking "Accept," you confirm:

  • You are at least 21 years of age
  • You are a qualified researcher or laboratory professional
  • You understand these products are for research purposes only