Thymosin Alpha 1 (10mg)

Original price was: $120.00.Current price is: $110.00.

Thymosin Alpha 1 (10mg) is a research-use product for laboratory studies involving endocrine signaling, hormone-related pathways, and peptide workflow design.

SKU: YPB.231 Category:

Description

Thymosin Alpha 1 (Tα1, Thymalfasin) is a 28-amino acid peptide originally isolated from bovine thymosin fraction 5 by Allan Goldstein’s laboratory in 1977. It is produced endogenously by thymic epithelial cells and represents one of the primary thymic hormones involved in T-lymphocyte maturation and immune competence establishment. It was the first thymic peptide to reach clinical use and remains extensively studied in immunology research.

Why Researchers Select Thymosin Alpha 1

Tα1 modulates both innate and adaptive immunity through multiple mechanisms: it promotes T-cell differentiation via TLR signaling pathway activation (particularly TLR2 and TLR9), enhances NK cell cytotoxicity, stimulates dendritic cell maturation, and upregulates MHC class I and II expression. It has been investigated as an immune adjuvant in infection models, in cancer immunology for its effect on T-cell exhaustion reversal, and in autoimmune research for its tolerogenic properties at specific concentrations.

Common Research Applications

  • T-lymphocyte differentiation and maturation studies
  • TLR2/TLR9 signaling pathway research
  • NK cell activity and innate immune modulation
  • Dendritic cell maturation and antigen presentation studies
  • T-cell exhaustion and immune restoration models

Molecular Profile

  • Sequence: Ac-Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser-Glu-Ile-Thr-Thr-Lys-Asp-Leu-Lys-Glu-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-Asn
  • MW: ~3,108 g/mol | CAS: 62304-98-7 | Purity: ≥98% HPLC

For Research Use Only. Not for human or veterinary use.

Additional information

Weight 0.2 lbs

Storage Instructions

All our research peptides are manufactured using a lyophilization (freeze-drying) process. This method is designed to maintain product integrity and allows vials to remain stable during shipping for approximately 3–4 months.

Once a vial is reconstituted with bacteriostatic water, it should be stored in the refrigerator to help maintain stability. Under these conditions, reconstituted material is generally considered stable for up to 30 days.

Lyophilization is a dehydration technique in which compounds are frozen and then exposed to low pressure. This causes the water in the vial to sublimate directly from solid to gas, leaving behind a stable, crystalline white structure. This powder can be kept at room temperature until reconstitution.

Upon receipt, products should be stored away from heat and light. For short-term use, refrigeration at approximately 4°C (39°F) is suitable. For long-term storage (several months to years), vials may be placed in a freezer at approximately -80°C (-112°F). Freezing is the preferred method for preserving product stability over extended periods.

⚠️ Important Notice: These products are intended for research use only. Not for human consumption.

Certificate of Analysis

Every batch undergoes rigorous third-party laboratory testing to verify identity, purity (≥98%), and quality before release.

View Certificate of Analysis
Third-Party Verified ≥98% Purity HPLC & MS Tested
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⚠️ Research Use Only — Legal Acknowledgment

All products on this website are sold strictly for in vitro research and laboratory use only.

  • Not for human or veterinary use, consumption, or application
  • Not FDA-approved to diagnose, treat, cure, or prevent any disease
  • Buyer assumes full responsibility for legal compliance in their jurisdiction

By clicking "Accept," you confirm:

  • You are at least 21 years of age
  • You are a qualified researcher or laboratory professional
  • You understand these products are for research purposes only