Sermorelin (10mg)

Description

Sermorelin is GHRH(1-29)NH₂ — the biologically active N-terminal 29-amino acid fragment of endogenous human growth hormone-releasing hormone. As the shortest GHRH fragment retaining full receptor binding and GH-stimulating activity, it serves as the foundational reference molecule for GHRH receptor pharmacology and somatotroph biology research.

Why Researchers Select Sermorelin

Unlike modified GHRH analogues (CJC-1295, Tesamorelin), Sermorelin is structurally closest to the endogenous GHRH signal and has well-established pharmacokinetic data from decades of clinical and preclinical investigation, including FDA-approved diagnostic use. This makes it the preferred baseline comparator when studying GHRH receptor binding kinetics, somatotroph desensitization, or GH pulse physiology. Its short half-life (~10–20 minutes) models the natural episodic GHRH signal.

Common Research Applications

• GHRH receptor binding kinetics and affinity studies
• Somatotroph GH secretion response characterization
• GH deficiency and somatotroph reserve models
• Baseline comparator in GHRH analogue studies
• Neuroendocrine GH pulse physiology research

Molecular Profile

• MW: ~3,358 g/mol | CAS: 86168-78-7 | Purity: ≥98% HPLC

For Research Use Only. Not for human or veterinary use.