GHK-Cu (50mg)

Description

GHK-Cu (copper tripeptide; Gly-His-Lys·Cu²⁺) is a naturally occurring human plasma tripeptide that binds copper(II) ions with high affinity. First identified by Loren Pickart in 1973 as a liver cell growth factor in human plasma, GHK-Cu has since been studied extensively in wound healing, collagen synthesis, and tissue remodeling contexts. The 50mg quantity suits in vitro collagen synthesis assays, antioxidant studies, and preliminary wound model experiments.

Why Researchers Select GHK-Cu

GHK-Cu activates multiple wound-repair and remodeling pathways: it stimulates TGF-β1 receptor expression and collagen synthesis in fibroblasts, activates metalloproteinases (MMP-2, MMP-9) for ECM remodeling, and acts as an antioxidant by sequestering free copper ions. Its copper-chelating property also provides SOD-mimetic activity. In genetic research, GHK has been observed to reset gene expression patterns in aged tissue toward younger profiles — making it a reference compound in aging-related ECM biology.

Common Research Applications

• Collagen I and III synthesis stimulation in fibroblast models
• ECM remodeling (MMP activation and regulation) studies
• Antioxidant and copper-mediated ROS scavenging research
• Wound healing mechanism and keratinocyte proliferation studies
• Gene expression profiling in aging tissue models

Molecular Profile

• MW: ~340.4 g/mol (free tripeptide) | CAS: 49557-75-7 | Purity: ≥98% HPLC

For Research Use Only. Not for human or veterinary use.