Epithalon (10mg) 
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Epithalon (10mg)
Original price was: $100.00.$39.00Current price is: $39.00.
Epithalon (10mg) is a research-use peptide for laboratory studies involving longevity-related models, cellular aging workflows, and structured peptide investigation.
Description
Epithalon (Epitalon; Ala-Glu-Asp-Gly; AEDG) is a synthetic tetrapeptide developed by Vladimir Khavinson’s laboratory from the natural extract Epithalamin isolated from bovine pineal gland. It is one of the most studied compounds in biogerontology research, primarily for its documented ability to activate telomerase (hTERT) in somatic cells in vitro — a mechanism linking it to cellular aging and replicative lifespan research.
Why Researchers Select Epithalon
The primary research significance of Epithalon lies in its telomerase activation: in cell culture studies, Epithalon has been observed to increase hTERT expression in human fetal fibroblasts and retinal epithelial cells, extend replicative potential, and maintain telomere length over more population doublings than control cells. It also influences the circadian-pineal axis — research has shown modulation of melatonin synthesis rhythm — and exhibits antioxidant properties in aging model systems. Published work from Russian gerontological institutes covers over 30 years of investigation.
Common Research Applications
- Telomerase (hTERT) activation and telomere biology studies
- Replicative lifespan extension in somatic cell models
- Pineal gland and circadian rhythm regulation research
- Antioxidant effects in aging tissue models
- Epigenetic bioregulator and gene expression studies
Molecular Profile
- Sequence: Ala-Glu-Asp-Gly | MW: ~390.3 g/mol | CAS: 307297-39-8 | Purity: ≥98% HPLC
For Research Use Only. Not for human or veterinary use.
Additional information
| Weight | 0.2 lbs |
|---|---|
| Dosage | 10mg, 50mg |
Storage Instructions
All our research peptides are manufactured using a lyophilization (freeze-drying) process. This method is designed to maintain product integrity and allows vials to remain stable during shipping for approximately 3–4 months.
Once a vial is reconstituted with bacteriostatic water, it should be stored in the refrigerator to help maintain stability. Under these conditions, reconstituted material is generally considered stable for up to 30 days.
Lyophilization is a dehydration technique in which compounds are frozen and then exposed to low pressure. This causes the water in the vial to sublimate directly from solid to gas, leaving behind a stable, crystalline white structure. This powder can be kept at room temperature until reconstitution.
Upon receipt, products should be stored away from heat and light. For short-term use, refrigeration at approximately 4°C (39°F) is suitable. For long-term storage (several months to years), vials may be placed in a freezer at approximately -80°C (-112°F). Freezing is the preferred method for preserving product stability over extended periods.
⚠️ Important Notice: These products are intended for research use only. Not for human consumption.
Certificate of Analysis
Every batch undergoes rigorous third-party laboratory testing to verify identity, purity (≥98%), and quality before release.
View Certificate of Analysis
